Thanks for your reply, Christine. Our ENT prescribed liquid prednisolone, which has helped to somewhat reduce the tongue swelling. We continued radiation yesterday, and the swelling has not increased; however, we noticed redness and some white patches on the tongue and palate. Our radiation and chemo oncologists feel this is thrush, caused by our first chemo treatment with cisplatin 5 days ago. My wife is was prescribed clotrimazole lozenges, which have reduced the patches in her mouth.