Kelly, I have no idea if this will help or not as I am very new to this whole thing, but I wanted to at least mention it. I went to Wake Forest Baptist Comprehensive Cancer Center on 2/20 to be evaluated for oral scc tongue cancer. The treatment plan they came up with was for surgery in 2 weeks. Meanwhile, they put me in a clinical trial. This clinical trial involves the drug Tarceva, which was previously used in patients with non small cell lung cancer to slow the growth of the cancer. Well, in this study, tarceva is supposed to stop the growth of scc and even shrink the tumor. I think they said that the majority of their patients had seen a reduction of at least 70%. I have been on it a little over a week and the tumor on my tongue has shrunk considerably. The reason I am mentioning this is that from what I understand, and again I am new at this, the cancer in your brothers lungs is really SCC since it metastized (sp).from the original cancer. Maybe this drug could help him since it is being used with scc in a clinical trial right now, the scc seems to respond well to it and it has been approved for lung cancer as well. I am being treated at Wake Forest and my Oncology and hematology Dr who is heading up this trial seems to be very compassionate and caring. I believe she will help if she can and if she personally cant, she may have information as to who can. I really hope I am not sending you on a wild goose chase as thats the last thing you need, but I have this information and have to share it with you if there is the slightest chance it may help. I really really hope it does. It's worth a shot anyway. My prayers are with you and with your brother. Keeping my fingers crossed. If you would like the contact info please send me a PM. If you need any more information, please let me know.