I had Induction chemo, which has been around for 25 years, with the same TPF chemo that did not go well, and for that reason it is controversial due to adverse reactions that can delay real curative treatments, which is radiation and surgery, but it is very effective, especially Lyrnx cancer, where it was initially used for voice preservation to avoid invasive surgery, but the overall survival is not changed compared to other treatments, I believe. Studies shows HPV positive tumors to respond very well to Induction, and are now adding Erbitux to it as well. Chemo makes radiation work better, and acts as a radiosensitizer. It can improve radiation, depending on chemo used, anywhere from 2-30 percent, so each are different. Cisplatin is gold standard, but carboplstin is said to be almost as
effective, with less side effects, and less toxicity on the kidneys.

Sally has some good advise on treatments. There are prescription, and OTC medication to help with pain, oral care, skin care, and adequate nutritional advise to maintain your weight, and hydration, which are most important. Good luck.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs