Lyn

Karen and I basically agree to disagree on this HPV Erbitux issue but her last post overstates her position IMO. While not a clinical trial, my comments are based on a study of 49 patients with Erbitux and HPV. It is evidence, just not conclusive. But there is no conclusive evidence that Erbitux does work with HPV either. I can't let an overbroad statement about Erbitux go uncontested on the forum.
We discussed it at length (5 pages) in this thread
HPV & Erbitux As I stated in that thread, the Bonner trial proves nothing about HPV & Erbitux. While you can extrapolate and make a good guess, it is actually less evidence than the 49 patient study IMO since that study did not track HPV status as Karen admits. Plus I actually had Erbitux.
No need to repeat all the points in that thread as we all said our piece.

I hope the Erbitux works for you. I am about to start my third time of chemo and my MO won't even consider Erbitux for my treatment this time either. Since you were also a smoker, your cancer may be more resistant than normal. Here is a study suggesting that but it only had 30 patients
EGFR P-GP Smoking

Charm

Last edited by Charm2017; 09-23-2012 05:47 PM. Reason: toned it down

65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13