I read the prior thread where Jamos was debating joining the Cisplatin/Cerbitux with Rad trial. I have been presented with the same option, but there are pros and cons to both, so I would appreciate any input. I'm not sure where, but I thought I read somewhere that Cerbitux wasnt as effective on HPV positive SCC (yay- got results of P16 today and it was pos); so there's the "con" on that. Pros, QOL, less side effects. For Cisplatin, some cons are side-effects, QOL, hearing issues and with neuropathy in extremities; something that my family seems susceptible to.
If I do the trial, and get the Cerbitux, and there are no positive indications that its working while i'm in treatment, and I want to, they will Not switch me off of it. (only way out of trial is if there is Actual Provable Regression/Damage being done by Cerbitux.)
My thought is to Not enter the trial, but request the Cerbitux, hoping that it will be effective even though I am HPV+, and I will get to enjoy the "pro's" of Cerbitux, And, if there isn't progress, i can go to the Cisplatin.
I know that was all pretty convoluted, so good luck figuring it out! But if any of you coud get through without your head spinning, and you want to please chime in with a thought or opinion, I would be grateful. I told them I would have an answer Monday, so I have some time to learn and sort through.
As always, thanks in Advance!
Lyn

Stage 4: Mid-line BOT primary; Left Lymph Node 4-5cm HPV+
Chemo/Rad 10/08/12; 3 big doses cisplatin
Updated 10/16 refusing Cisplatin; due to side effects
Considering Carboplatin; discussing with doctors.
Corp. Trainer- South New Jersey
Life is What Happens When You're Busy Making Other Plans.