Norman, I'm sorry to hear about your brother. We are going through this with my husband. We got 3 opinions. First, Mayo Clinic, wanted to operate, leaving my husband with a permenant swallowing problem. Second (MD Anderson) and Third (Univeristy of Chicago) both wanted to to chemo, then chemo radiation. This approach appealed to us as it gave my husband the best chance for a good swallowing outcome, plus the induction chemo gives him coverage for any microscopic, unseen metasis. Anyway he goes, I would strongly advice getting at least two opinions, three better...before committing to a treatment plan. Once the train in on the tracks, he needs to commit 100%.