Colette, sorry to hear about your troubles. I can relate. After all the various pills, potions and suppositories - which I hasten to add didn't work very well - I got the advice that did the trick from, yes, my RO's nurse.
To be blunt: a box of rubber gloves.
Not easy, but the, er, hands on approach pretty much saved my life.
Best of luck with whatever strategy you decide to try.