Hi Angelia,

I was told that "peripheral neuropathy" is a possible side-effect of Cisplatin. It's basically nerve damage that shows up in one's extremities such as feet and fingers and can manifest as tingling or numbness. Hearing loss/damage is also possible for the same reason. It's worth noting that radiation treatment can also do some damage to the nerves in the spine, but this, too, is hopefully temporary.

Peripheral neuropathy tends to show up in the extremities because these are the longest nerves. Some people have this reaction almost right away. In my case I only had three doses of Cisplatin, so a relatively low dose (although that dose is probably common on this site due to the type of cancer treatment represented here). I did not have any initial poor reaction so they "signed off" that I was okay with it. But months later I believe I developed some peripheral neuropathy in the soles of my feet - sort of a feeling as if the skin of my soles was "too thick". And now, ten months from treatment, I've realized I've had some hyperacusis, and maybe now some minor tinnitus showing up.

The neuropathy hopefully is temporary, as these nerves can regenerate themselves. I've been told to massage my feet - basically to do anything that encourages blood flow, as this will also encourage nerve regeneration. It's worth noting that my mother has peripheral neuropathy in her feet at 72, without any cancer treatment, so it may also be inherited. Or, in her case, a lifetime of exposure to ceramic glaze ingredients as an artisan may not have helped, either. Oh, and my father has tinnitus, but he's also a lifetime artisan/woodworker/builder, so has abused his hearing tremendously.

My medical oncologist didn't mention the possibility of late-onset side effects, but I have since seen several references to the possibility.

I guess these are relatively minor annoyances, but of course, we'd like to be as normal and healthy as possible!

I've recently started jogging and doing yoga. It's going well. I've never been a "runner" but it's a very easy way to get a cardio workout, if you start gently so you don't injure yourself.

Good luck!

-Seth