My parents, poor impoverished uni students that they were, could not afford a honeymoon. So they volunteered to be subjects in a British research project on the common cold. They were taken to a holiday camp that had been especially isolated for the project, were given full use of the facilities but were only allowed contact with each other. Then they were injected with rhinovirus followed closely by the potential cure. Perfect honeymoon had the researchers actually managed to find a cure (and probably a nobel prize and knighthood for the researchers).

That was 1958