J Scott

It took about 2 weeks to notice an improvement but it was small. It wasn't until my doctor bumped me up with dosage that it was really noticeable. It's the blood tests that tell the story. My endo feels she gets better results with Levoxyl than from Synthroid but they're supposedly the same according to their web sites.
Finally, I am trying an experiment where I take my Levoxyl at night before bed rather than having to wait an hour or more after taking it in the morning before having breakfast. I was getting up at 4 am and taking the pill just so I could eat a regular breakfast (okay - not eat, but syringe in two cans of jevity mixed with coffee) with my wife.
I've had zero problems and in fact like it better. The literature indicates they recommend it in the morning before breakfast only because some participants in the FDA study approving it had difficult sleeping if they took it at night. I sleep even better now. My next blood test will be the proof of whether it's working as well.
Charm