Medically speaking there is no comparative study that I am aware of showing one method is better than the other but it appears just from the posters on this site that the ones that have had it weekly do not suffer as much in the nausea dept and don't seem to complain as much about the ringing in the ears and permanent hearing loss as the ones like me that got the 3 big doses.

I was just on a panel discussion at Moffitt and I talked to Moffitt's head of Chemo and they still go with the 3 doses.

This is just my opinion but since your Dad has a tobacco history I would go with their recommendation of the big 3. Do tell him to listen for "ringing" in his ears or anything that sounds different in his ears and if he experiences that to tell his chemo doctor asap as that can and usually does lead to permanent hearing loss. Most that have a rough time with Cisplatin are often switched to Carboplatin for their 3rd dose or they just don't do a 3rd dose.

I might also recommend that he ask for a pre Cisplatin Tx hearing test so that he can establish a hearing base line to better establish any hearing loss post Tx.