Charles,

Yes it does appear that HPV+ SCC responds better to the same Tx and (therefore) has less of a chance of recurrence but the unanswered question is how much less treatment can a HPV+ patient receive and still kill the cancer noting the many different factual patient presentations one could encounter. There haven't been any studies trying to answer that question yet. Dr Trotti's may be the first to give us some direction but that will take years. Until then it would just be pure speculation for anyone to suggest a lesser Tx and the patient would be nothing more than a guinea pig. Do I feel that one day there will be 2 different treatments for HPV+ vs. HPV- SCC, yes but that doesn't mean I would want to be one of the one test subjects.

Re the surgery, you are correct that I didn't have a ND and that was Moffitt's approach even before I was confirmed HPV+. If I had listened to 3 of the 5 doctors I saw leading up to Moffitt, I would have had some form of a ND.

Also don't beat yourself up on the "who did it come from" question because you will most likely never get that answer. Just appreciate that fact that you are unique enough to have allowed the HPV virus an unchallenged welcome into your cellular structure. lol