shelly,
my hubby went thru 3 rounds of chemo...5 days a week X 24 hours a day, then would have 2 weeks off. now he is doing radiation X 5/once a week chemo.

in his experience...the once a week is much more tolerable. he would do the chemo 1 week (5 days) but it would take him a week to recover, and by the time he started feeling better, it was time to do it all over again.

at this point he has alot of side effects but it is mainly due to the radiation. i can not imagine him doing a week of radiation and chemo concurrently.

but everyone is different.