People are hesitate to take medication on a regular basis for something they may or may not get and naturally worry about potential side effects. Vaccines might be an easier "sell" as many are already required.

Serious trust issues due to changing and sometimes contradictory medical advise.

The Blame Game - When medical establishment does not have an explanation, blaming the patient for something she/he did or didn't do (poor diet, weight gain, etc.) and then discovering that it had nothing to do with getting cancer, does not instill trust.

Do we need more research funding for brand new approaches? Money for researchers not tainted by old assumptions? Why are certain cancers more popular and therefore receive more support and money? Obviously these are not original ideas.

Honestly with the public might help - stating that this is very complex and you can do everything "right" and still get cancer.
Lottie