I question the essential validity of the study, due to the fact that a different patient population (older, poorer performance status) was used for the weekly dose, and younger, better performing patients were used for the 21 day regimen. A more valid study would have been to use similar patient populations in each treatment modality, then compare.

My CCC uses the weekly regimen as its primary therapeutic methodology, and has had good results.

I am also curious about the low (50% and 40%) Complete Response Rates. That is significantly below what is acheived at most CCC's these days, based upon my reading. Would be interesting to see what the TMN and location characteristics for the test population.

Also tough to draw too many broad conclusions, since test population was small.