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#61702 09-06-2007 09:50 AM
Joined: Aug 2007
Posts: 580
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Kevin,

Pilocarpine is a great saliva stimulator.
Check out this website for complete information.
http://www.drugs.com/cons/Pilocarpine.html.
It is very improtant to drink extra fluids while taking it.

Cheers,

Mike


Dentist since 1995, 12 year Cancer Survivor, Father, Husband, Thankful to so many who supported me on my journey so far, and more than happy to comfort a friend.
Live, Laugh, Love & Learn.
#61703 09-06-2007 03:22 PM
Joined: Mar 2002
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Patient Advocate (old timer, 2000 posts)

Joined: Mar 2002
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Many who try pilocarpine do not get much help from it. While it may get a bit more saliva for you, I think that the point that everyone ignores is that when the gland is dead, nothing so far brings it back to life and production. Pilocarpine's course of action stimulates ALL the possible moisture producing micro glands in your mouth (which are numerous -think thousands of tiny pores- and do not just include the major salivary glands but those single pores that cover much of the mucous membranes of the oral environment). Note though that it is not a localized effect, and plan on sweating like a bull in heat. My personal attempt at using this stuff left me with more than sweaty pits, palms, and more private parts. It was a genuinely uncomfortable experience for the minor oral benefit. I will spare you articulating the BO issue that accompanies copious perspiration. Your mileage may vary......


Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
#61704 09-06-2007 03:32 PM
Joined: Aug 2007
Posts: 580
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I have to say Brian, that has to be the most humerous post I have seen on this site! All true.
But your description nearly broke a few ribs, I haven't laughed that hard in years.

Take care,

Mike


Dentist since 1995, 12 year Cancer Survivor, Father, Husband, Thankful to so many who supported me on my journey so far, and more than happy to comfort a friend.
Live, Laugh, Love & Learn.
#61705 09-07-2007 01:02 AM
Joined: May 2007
Posts: 622
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Thanks Mike - I visited that site when the doc first told me about the drug. I keep my water bottle handy and I am still in the neighborhood of 4 liters/day.

I must be one of the semi-lucky ones. The pilocarpine has helped some, but some is better than none and the other side effects you mention Brian are not quite that out-of-control for me. <<BIG GRIN>>

Kevin


18 YEAR SURVIVOR
SCC Tongue (T3N0M0) diag 06/2006.
No evidence of disease 2010
Another PET 12-2014 pre-HBO, still N.E.D.


�Remember to look up at the stars and not down at your feet. It matters that you don't just give up.�
Stephen Hawking
#61706 09-07-2007 05:44 AM
Joined: Nov 2006
Posts: 95
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Posts: 95
My husband completed his radiation on 12/05/06. He was told he would probably lose his entire full beard permanently, but it is back except for one tiny area. He was told that he would not lose hair on his head, but he did have quite a lot of fall out. That has also now seemed to have stopped. He has also been taking some vitamins to help with the hair situation. He had a follow up exam yesterday & the doctor indicates he looks great, he is gaining weight, his throat looks good. He has another PET scan coming up in October, but first CT and PET scans were fine - Great News. Good luck with your recovery


Barbara S
C/G to Michael age 64, stage 1 base of tongue SC cancer and a stage one for a couple lymph nodes, diagnosed 09/12/06, IMRT radiation 10/24/06 to 12/05/06 , last PET / CT scan 11/7/11 - still cancer free!!!
#61707 09-09-2007 01:37 PM
Joined: Jun 2007
Posts: 718
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I'm curious if Evoxac works similarly or different to Pilocarpine. Does anyone have experience with Evoxac that they could share regarding the saliva issue?


Margaret
----------
C/G: Husband, 48 (at time of dx)
Dx 5/18/07 SCC, BOT, lymph node involvement. T1N2BM0. (Stage 4a, G2/3)
Tx 6/18 - 8/3/07, IMRT x 33 Cisplatin x3 (stopped after 1st dose due to hearing issues). Weekly Erbitux started 6/27/07 completed 8/6/07.
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