The green bottle has a protein in it that really cuts into bio films, which are necessary for plaque and calculus to form. I use it regularly along with the matching PBF toothpaste, especially at night. The blue bottle is the original formula, and it does not have this proprietary protein in it, but it seems to make my mouth feel slippery and all a lot longer. I use it a couple times during the day. Prevident 5000 Rx fluoride toothpaste right before bed each night, to try and protect things as much as I can. I use my trays about once a week.

Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.