I think it's a great idea. I went to Naples exactly 2 weeks after my last treatment. I told my med onc about it and he gave me a raised brow look, forewarned me how I might feel, but basically said it was up to me. There were a few rough spots, but for the most part, it was much needed. I ate my first steak on vacation, and although I couldn't taste it, was very proud of the accomplishment. My husband also upgraded to first class on the flight with miles, so that was also nice. My only recommendation is that the place you rent has working air conditioning. My mother in law(where I stayed) never turned hers on, and there is nothing like being nauseated in the florida heat. I had a few bouts and could have used a cool place to lay down. Regardless, I think it is a good thing to plan for. The mind is powerful. If I listened to my MO, I may have stayed at home, in cold Michigan mind you, drinking my boost and wallowing in my sorrow.