There is some info re severe allergic reaction to the MAB Erbitux. This reaction occurs within minutes of the infusion. It is not the more normal skin rash.

http://www3.niaid.nih.gov/news/newsreleases/2008/cancerdrugallergy.htm

Hopefully, they devise a test for this soon, the alternative is to be extremely careful the first time you are given Erbitux. How many MO's hang around in the chemo lounge?, exactly!

It still irks me that although I told my MO that I might be allergic** to Erbitux and we agreed on a test dose it did not happen and the result was an anaphylactic shock.

** I worked with mice (Erbitix is a mouse derived antibody).

Hope this info is useful for somebody.

M


Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.