The bottom line is not the choice of drugs, even this one which is showing some promise in the world of cancer treatment after its horrible issues with birth defects in its past, but that conventional treatments have not brought him to the clinical outcomes that are needed for him to survive. Given that situation, I think that I personally would try what there was available to me, even if not completely proven as with Thalidomide. The issue that needs to be considered is while this experimental treatment is being used, what are the quality of life consequences and how do those balance with the potential for success? This is a really difficult choice. Is he mentally and physically strong enough to keep up the fight? If so, I would say...bring it on. It's at least a shot that may buy valuable quality time with people that he loves.