There is a page that talks a lot about these kinds of monoclonal antibody drugs at the link on the main site http://www.oralcancerfoundation.org/treatment/targeted_therapies.htm

Having said that, Erbitux is usually used in combination with other drugs and not as often as a mono therapy by itself. It method of action is to stop the replication of cells as opposed to killing them like we normally think of chemo drug doing. Those that have posted here that were having positive results to certuximab ( Erbitux) seem to have the greatest degree of the rash side effect from it. Dealing with this rash is discussed in a PDF document on the bottom of that same page. I do not have any personal experience with it, but I expect that you will soon hear form other posters that do.

It is a relatively new drug to head and neck cancer use, and there isn't really very long term data on it (more than what was required to get the extra indication from the FDA) The longest term data is in the realm of colon cancer where it was first approved for and used.