Thanks, Minnie,
Is your running problem because it causes pain to come down hard on your leg? or is there some other lack of function? Sadly, I never did run, and whether or not I have the surgery, I have other leg and foot issues that keep me from skiing or playing tennis. I AM a little concerned about these other issues, but I don't think that either will interfere with the other, as long as I don't have some sort of nerve damage from the surgery.
I even asked my orthopaedist about how the loss of the fibula would affect an eventual knee replacement if I needed one, and he said that it would not affect it at all.
How is your other leg wound coming along? I know that you were having healing issues from the donor site for your recent tongue surgery. I hope you are over that hump finally!