What are the studies on Smoking realated vs HPV induced causes, differences in response to treatments and odds of reoccurence. My husband never smoked, rarely even has 1 drink and continues to develop complications. His esopaghaus is totally blocked from a radiation induced 4inch scar. He is having a rendevous procedure done at memorial Sloan- Kettering this week. The local ENT said he would be on a peg tube for the rest of his life but at MSK they feel there is a 90% chance they will be able to dialate. Of course as his wife and caregiver I'm terrified that this cancer is going to reoccer.