"Above & Beyond" Member (500+ posts) Joined: Jul 2005 Posts: 624 | Peripheral neuropathy may or may not go away over time. There are medications which supposedly can help, you would need to talk to a neurologist about this. Some people are helped by low doses of primadone (an anti-seizure drug) or similar drugs, but always after careful evaluation by a neurologist. The peripheral nerves do have some ability to regenerate.
Cisplatin is one of the worse offenders in causing this side-effect, some of the taxanes as well (e.g. Taxol). Our MO gave my husband carboplatin instead of cis- as he already has some problems with essential tremor of his hands (controlled by primadone) -- both our MO and RO said several studies have found no significant difference in efficacy as radiosensitizers in HNC chemoradiation between the two platinoid drugs, but cis- is still given to most patients as it has the longest clinical history and results data.
Gail
CG to husband Barry, dx. 7/21/05, age 66, SCC rgt. tonsil, BOT, 2 nodes (stg. IV), HPV+, tonsillectomy, 7x carboplatin, 35x tomoTherapy IMRT w/ Ethyol @ Johns Hopkins, thru treatment 9/28/05, HPV vaccine trial 12/06-present. Looking good!
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