Most major cancer centers now allow self-referral, and MDACC is one of those. I recommend that you include her current treating staff in the loop for many reasons, not the least of which is common courtesy. They know in detail what's happened up to this point and have some intimate knowledge that will be helpful to any new team. They also have all the necessary records, scans, etc. Any doctor worth his salt isn't going to be offended by a patient asking for a second opinion or a change of venue. It happens often enough, and does not necessary mean a personal affront or lack of faith in the current team. The contact number at MDACC is 800-392-1611. They have several doctors who generally are the first screeners of new patients. From those docs you would get assigned to the appropriate treatment team. Since she is having all this done in the same state, that should mean few insurance hassles, but be prepared for some BS from the company that you will have to deal with. The MDACC web site can be entered through the resources page on the main OCF nav bar, and there is more information on their site that you may wish to review before you make the initial call.