I'm confused about something here. If one has the mandible radiated and then non-radiated bone from the leg transplanted, doesn't it make it harder for the transplant to be successful since the vascularity of the already radiated area where the new bone is going has been compromised?

Or, is the new bone transplanted and then the area radiated? That would seem to create a similar situation in which blood flow to the tranpslanted bone and surrounded tissue is reduced? Sorry to be so obtuse. - Sheldon