I am currently part of a phase III post-treatment chemo-prevention study at M. D. Anderson that includes acutane, interferon and vitamin E. I'm one of the controls, so I don't get the meds. But I wanted to post this because I wanted you guys to know that vitamin E is in fact being studied in a clinical setting as a co-agent in chemo-prevention regimen.

Incidentally, in my research into this stuff I have found a favorable possibility that vitamins may be helpful in a preventative mode. However, once you have active disease there appears to be no benefit. I use words like favorable possibility and appears, because there's not a whole lot of proven definative stuff out there. My gut feeling is that mega-dosing is not a good idea whether you're healthy or sick and that any benefit obtained from supplements is very modest. I have reduced my own supplement intake to a multi-vitamin containing 100% of the RDA with an extra 500mg of vitamin C once a day.

-Brett