I did Amifostine through most of my treatment though they did not follow all those instructions for administration (gave it through a port) which may have made the nausea, which I had almost every day when I had it, much worse). I found the nausea lasted for about 3-4 hours after.

I think the "remain quiet" and "stay quiet" in the instructions Gail gave are really informative and important since when I vomited from the Amifostine, it was almost always because I had just stood up suddenly or engaged in some other form of movement. The good news is that that meant I never needed to vomit when I was under the rad machine wearing a mask (well-actually only once, and that was at the very end when I was just yakking all the time) because I was lying so still. Is your mom's vomiting tied to some period of movement beforehand (say, returning home after radiation or something?)

Anyway, after all that sticking it out with the amifostine, I'm not actually sure how much it helped me. I still have some saliva-but that should have been true anyway as they were able to spare one of my parotid glands. If I had been told it only has a 50% chance of working at all, I never would have stuck it out for so long.

Nelie