Hi Billy, I will address the constipation first because I had alot of trouble with it. My doc suggested Senekot S as a stool softener. It kind of worked until I went on the narcotics. Nothing worked after the chemo, and nothing worked when I used the morphine pills. It wasn't like I felt constipated. I didn't feel anything in my bowels. I finally made this clear to my docs and they said why didn't you say something. I thought I had but that is when they put me on polyethylene glycol and a mild suppository. I needed the suppository to tell my bowels to work. I tried the magnesium sulfate at first but once the sores came up in my mouth there was no way. There is a brand name for the Poly glycol and it is now over the counter. I see it advertised on TV all the time I just can't remember the name of it. You should consult you docs before taking any of these. And you have to keep up your fluid intake. Amy gave you all that advice. It is trial and error. i was almost finished with treatment when I finally got it under control.