KristyN, Hi- Just wanted to share that my husband has been on Erbitux since July and the only real side effect that we can identify thus far is the rash. Since he is totally on PEG, we can't speak to whether the Erbitux might change his sense of taste-but I don't remember reading that as a side effect. I would venture a guess that the radiation is working on your taste buds at this point. Amy