debated whether to post given i only just started on this patch monday evening. figured i can post again if anything changes. started at 25 mcg and had it bumped today to 50 mcg. no fatigue nor nausea and oxycodone had given me nausea in beginning but it got better. not finding it terribly efffective for my pain given i'm also still taking 15 mg of oxycodone every 3 hours and i still have periods where there is serios pain. pretty sure i am at a phase (2 rad sessions left) where pain is still increasing fast so i have to increase meds fast or faster. instinct says at higher doses this will work well. hope thats somewhat helpful