My husband has a lot of trouble with nausea as well. He has tried various meds, and more than one at a time. For instance, he was taking Zolfran, Compazine and Ativan on a rotating basis, as the doc explained that they all help with nausea, but they work in different ways from each other, so it is not as you are overlapping. But one of the things we didn't realize at first was that he should take the meds on schedule, i.e. every 4 hours or whatever the recommended allowance is, versus waiting until a nausea spell came on. This may seem a simple thing that we should have known but we didn't. He still has nausea problems but they seem to subside a little on the third week after the chemo, which he gets once every 3 weeks. Right now he taking Reglan and Ativan only but may start back taking the Zolfran next week after he gets chemo on Tuesday.
Wish you luck.
Michele