Sherry (AKA Delores ;-),
I take it he's getting Cisplatin - that's usually a three week treatment protocol. It will get slowly better until the next Tx then he gets to start over. For me everything had a metallic taste and I had a chemical body odor for quite a while until that stuff was finally purged from my system. He MUST drink 2-3 liters of water daily to protect his kidneys from damage. My second round was much worse than the first. Much more nausea and synergystic effect with the radiation. Everyone is different though and his reactions may be much milder.

It's hard to say about the fatigue but it is a well known side effect of cancer treatment. It took me about a year before I was at 95%. The radiation is a bigger cause of fatigue than the chemo. Figure on a month of recovery for every week of radiation. Some folks here have worked through Tx - not me though.

I really don't think that the chemo is really doing much on it's own. It is an adjunct to the radiation which is the primary curative method. I would put my money on the radiation for shrinking those tumors.