PEG tubes can develop minor infections around them. This is essentially an issue of keeping the tube itself ultra clean and the entrance site through the abdomen clean as well. I developed a small infection with mine about the second month that I had it. I have to admit, at that stage of things I couldn't have cared less about many things including whether or not my PEG was clean. Some Bacitracin ointment for a few days on the area and it cleared right up. I do not think that fear of infection is a reason to not have a PEG. The benefits far out weigh the down side risks.