In my case I would say my "buds" began changing around week 3. The first notable loss was chocolate which I ate a lot of. I bit into a Hershey bar around week 3 and ran for the trash can as the taste was terrible. I simply could not believe it. Now, 16 months post Tx, I would say taste is somewhere between 90% to 95% back to normal and may be as good as will ever be. Chocolate still tastes terrible and I cannot tolerate the taste of beer or any other alcohol. Thank goodness I was never much of a drinker anyway. My taste for coffee was never really lost thank goodness as I would rather have coffee than any alcohol. Good luck and well wishes to your brother.

Bill D.