Dear HH, Please be aware that I am answering you as a caregiver to my husband-not a medical professional. My husband started on Erbitux in July after Carboplatin\Taxol failed to control his cancer. The Erbitux has not only controled the tumors, it shrank them. He has had to deal with the rash, as reported and the fingernail and toe nail lesions. He has been able to deal with that.His Chemo Doc cannot tell us how long John will be able to tolerate the Erbitux because it is too new. It sounds like your Mom may be at the point of deciding "quality of life vs. quantity of life", as the Doctor says, but it's hard to know if the Erbitux will give her 2 months or a year or more unless there is more deterioration in her physical condition than you have stated. I know you feel really helpless right now and there are no easy answers to your questions. Just know that many of us are feeling for you. Amy