Cynthia raises and excellent point about how previously calm rational people can become paranoid to the point of feeling like a psychiatric diagnosis is in order! I think we should include all caregivers and partners in this statement as well. Living with the "worry factor" is constant and at times overwhelming.
On a practical note, I would suggest someone go with your sister when the results are reviewed and ask the MD's to SHOW on the comparative scans what they are seeing, and offer an explanation. I would cross-check a surgeon's explanation against a radiation oncologist's and vice versa. If there is any doubt or big debate, ask if her case can be presented at tumor board and have her(and a trusted someone else) attend to hear the debate. If this is not allowed, ask for a representative from each speciality to meet with you.
Best of Luck,
Kim