Jim had Cisplatin and we were very lucky to get him through it without the nausea. The chemo nurse had me start him on the Zofran within a few hours after we got home and then to give it to him religiously every four hours until we were 24 hours past the chemo. Then I weaned him off increasing the time after each dose until he felt he was in the clear.

They told us to be certain we started him on the Zofran - regardless of whether he felt any nausea. You have much better luck if you can stop the nausea before it starts, rather than trying to stop it after it does.