Hi, my sister is taking cisplatin and 5-fu for her base of tongue tumor. Her nausea so far has not been that bad. If its effective we don't know yet but I can say that the pain has gone, where once it was unbearable and she also had a small lesion on the side of her tongue which has disappeared. Another common cocktail of chemo is Taxatere, 5-FU and Cisplatin. I have corresponded with a gentlemen who had success with the treatment when in conjunction with radiation. Good Luck.