Hi, Shelly, mucous and nausea are two very big and ongoing issues with this treatment. Many people will tell you that "you have to stay on top of it" Read that to mean- "Keep insisting that his Docs and nurses hear that he is having a problem and try different things to get it under control." Also, keep a good chart of the pain meds. he is taking- many of them can wreck havoc on one's stomach. How are you doing so far? Amy in the Ozarks