OC is the most effective weightloss programme I've ever been on, but it's the worst treatment. I lost 40kg (although learning to eat during lock-down has caused me to put on 4kg :D) I ended up giving away pretty much my entire wardrobe to friends and charity, then I hunted on eBay for new ones.
Please, if you can, keep us posted about the trial! I am very interested as to see which part you become involved in and what the results are in the long term. I know what I think, but I'm not a medical professional