Praveen, although I am a survivor of stage IV oral cancer, I am not a doctor. That said, in the four years I have been learning about this terrible disease, what you outline seems like the aggressive treatment that would be prescribed here. I am impressed that your brother is being given drugs to protect his white cells, which are generally a casualty of chemotherapy. From my perspective, it looks like he is receiving very good treatment, which I hope will ease your worry a bit. Pleae feel free to ask additional questions. If you have not already explored other parts of this extensive site, I recommend that you do. Finally, please let us know how your brother is progressing, and take note of the fact that I survived stage 4 treatment and am doing very, very well today.