After 2 major surgeries, radiation, and chemotherapy for my husbands buccal cancer.....he had his third reoccurrence. The doctor said huge strides have been made in treatment options..... with immunotherapy being very beneficial. So hubby is doing Opdivo every 2 weeks. After his 10th treatment, his CT scan was clear. He thought that meant he could stop treatments but the oncologist said he would be on it "a long time". With reoccurant oral cancer is the immunotherapy essentially "Palliative care"? Also, he is having a lot of trouble with the side effect joint/muscle pain. A rheumatologist would treat with steroids. But I have read that normal amounts are insufficient. Are there alternative treatments to high doses of prednisone? Any input is welcome. Diane