My husband had a leaking tube as well as granulation at one point in his treatment. The interventional radiologist looked at it and said he could replace it but it was complicated. It involved putting in a tube at a nearby spot, etc, etc. He sent us to a wound specialist who suggested doing what ChristineB said in her post above. The visiting nurse told us never try to clean the insertion point by rubbing it too hard. We should just dab it gently with some gauze, then put the cream on it and cover it with the drain sponge. Hope this helps.