Since your brother is in FL, why not try Moffitt? Thats one of the countrys top CCCs they are very experienced in treating OC patients. Im sorry but off the top of my head I cant think of anyone who has been to Mayo but Im sure some have over the years. OCF doesnt rate facilities, but we do talk among members on where they get treated.

Radiation is NOT always a once and done thing. I know of many who have been thru it twice. I even know 4 patients who have been thru it 3 times and survived. This is done on a case by case basis so it does not fit for every single patient.

As far as chemo being done afterwards, that is usually done for for palliative care only. Alone, chemo can shrink the tumor but its doubtful it can completely eliminate it.

As far as surgery goes.... I completely understand how invasive it would be and how it would greatly impact your brothers quality of life. I had a huge surgery (mandibulectomy) to remove half of my bottom jaw where the cancer had invaded my jawbone. This was a 10 hour operation that was very intricate and had to connect teeny tiny blood vessels. I cant imagine how difficult a surgery would be for what you explained your brother would need done. Now that would be a major surgery!

The only ways to completely eliminate OC are surgery and/or radiation w/ or without chemo. Anything else you come across may not be thru all the FDA trials where its readily available and successful in removing your brothers cancer... every teeny tiny cell.

PS... Please add your signature asap so its easier to understand whats going on with your brother and reply to your questions. Thank you!