I personally had my 2nd fibula free flap 2 years after my first surgery after radiation and after chemo. I am very happy with my results. Prior to the 2nd surgery I had an infection that lasted from 11/2013 until 1/2016. My only side effect other then the recovery/ pain has been the donor site. I just wish that I hadn't waited so long. Please discuss everything with your doctors. While everyday remains a challenge I am so thankful for being here to be able to "complain". Good luck and best wishes.