The symptoms you describe, tiredness, being cold, can be from the anemia, low hemaglobin. I have chronic anemia, hemaglobin ranges from 7.5 to 10. I'm never over that. I wear long pants, shirt, socks all day, even to bed from being cold. It's from treatment, which destroys RBC faster then they can be replaced, plus the compromised bone marrow where they are produced, doesn't make enough. . RBC picks up oxygen, hamaglobin, in the lungs, but there are not enough being made to attach, and be distributed in the body. Same thing with WBC. RBC have a life cycle of 90-120 days, and are continuously replaced by the body. If my hemoglobin gets lower than 9, I could get a Lance Armstrong shot lol, epogen or procrit, but during treatment, with active cancer, it's not recommended or used by some institutions, and if given when hemgaglobin is high, it runs the risk of speeding up cancer, increasing the size of tumor. If it gets under 8 or 7, I've been down to 6, I would get a blood transfusion. You can really get a transfusion if its under 10, depending on symptoms, hospital policy, doctor, but they also have their own risks. One is an increase of cancer recurrences, and seen a journal article of an increased HNC recurrence risk from 30% with no transfusion to 71% with one. As such, my hemaglobin gets up to 10 from one of the therapies, and goes down every three months, and need a shot or blood transfusion, and the same cycle continues, but they do help with quality of life.

Check your creatinine levels too, which measure your kidney function. Compromised kidneys can also cause anemia, low hemaglobin, plus others ailments, conditions.