Just remember the mouse may live or die but it never tells what is going on. smile

Many other studies are referenced in the footnotes if you want to dig deeper.

When my mother was in final stages of ovarian cancer we used Vioxx and Celebrex to reduce the blood supply to the tumors and it stopped the progression quickly and sustained it. Unfortunately it was too little...too late. We stopped 4 large brain mets that they expected would kill her within weeks. 9 months later she passed from stomach acid eating through the esophagus and aorta after her G-J tube came out and she didn't want it replaced.

SCC Stage IV, BOT, T2N2bM0
Cisplatin/5FU x 3, 40 days radiation
Diagnosis 07/21/03 tx completed 10/08/03
Post Radiation Lower Motor Neuron Syndrome 3/08.
Cervical Spinal Stenosis 01/11
Cervical Myelitis 09/12
Thoracic Paraplegia 10/12
Dysautonomia 11/12
Hospice care 09/12-01/13.
COPD 01/14
Intermittent CHF 6/15
Feeding tube NPO 03/16
VFI 12/2016
ORN 12/2017
Cardiac Event 06/2018
Bilateral VFI 01/2021
Thoracotomy Bilobectomy 01/2022
Bilateral VFI 05/2022
Total Laryngectomy 01/2023