Don, I believe the recurrence concern is for anything microscopic that was not removed during your surgery, killed during chemoradiation treatment, distant metastases, and secondary cancer from radiation, chemo, and those that are smokers that may be higher risk of a aerodigestive SCC cancer, other type cancers, possibly other type HPV cancers.

David, I think the antibody subject was brought up in the discussion with HPV Questions, I made a few months ago in After treatment Issues, and brought up about HPV-16 reinfection, new cancer, in the oropharynx, anogenital area, and read some develop antibodies for HPV-16, after exposure, if I have it correct. HPV-18, maybe, which is not as common in the oropharynx, and if 1% of HPV-16 is in the oropharynx, 18, is even more remote. HPV-16 in the cervic can have multiple infections fought off, which may be different in the oropharynx. I'm sure there is more than one theory, and keeps changing as more information is found, but would like to know, if anyone can get some written facts.