Thanks Paul.

Persistence is the name of the game in our medical system. It's unfortunate, but unless you're lucky enough to find a great team of physicians, you have to do a lot of legwork.

My brother did have a period of 5 years where he smoked 1-2 cigarettes a day, chewed tobacco, and drank socially. All that stopped about 7 years ago. Since ~2006, he just drinks socially.

I don't think tissue was saved. The surgeon did not send frozen section margins. The entire specimen was submitted. I wish I had known about the requirement to have frozen tissue saved. I can ask to see if they can do the test on the existing tissue.